Selective histone methyltransferase G9a inhibition reduces metastatic development of Ewing sarcoma t...
Selective histone methyltransferase G9a inhibition reduces metastatic development of Ewing sarcoma through the epigenetic regulation of NEU1
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Author / Creator
García-Domínguez, Daniel J. , Hajji, Nabil , López-Alemany, Roser , Sánchez-Molina, Sara , Figuerola-Bou, Elisabet , Morón Civanto, Francisco J. , Rello-Varona, Santiago , Andrés-León, Eduardo , Benito, Adrián , Keun, Hector C. , Mora, Jaume , Tirado, Óscar M. , de Álava, Enrique and Hontecillas-Prieto, Lourdes
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Ewing sarcoma (EWS) is an aggressive bone and soft tissue tumor with high susceptibility to metastasize. The underlying molecular mechanisms leading to EWS metastases remain poorly understood. Epigenetic changes have been implicated in EWS tumor growth and progression. Linking epigenetics and metastases may provide insight into novel molecular targ...
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Full title
Selective histone methyltransferase G9a inhibition reduces metastatic development of Ewing sarcoma through the epigenetic regulation of NEU1
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9054661
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9054661
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-022-02279-w
