A mixed-valent Fe(II)Fe(III) species converts cysteine to an oxazolone/thioamide pair in methanobact...
A mixed-valent Fe(II)Fe(III) species converts cysteine to an oxazolone/thioamide pair in methanobactin biosynthesis
About this item
Full title
Author / Creator
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS) , Park, Yun Ji , Jodts, Richard J. , Slater, Jeffrey W. , Reyes, Reyvin M. , Winton, Valerie J. , Montaser, Rana A. , Thomas, Paul M. , Dowdle, William B. , Ruiz, Anahi , Kelleher, Neil L. , Bollinger, J. Martin , Krebs, Carsten , Hoffman, Brian M. and Rosenzweig, Amy C.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
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More information
Scope and Contents
Contents
The iron-containing heterodimeric MbnBC enzyme complex plays a central role in the biosynthesis of methanobactins (Mbns), ribosomally synthesized, posttranslationally modified natural products that bind copper with high affinity. MbnBC catalyzes a four-electron oxidation of a cysteine residue in its precursor-peptide substrate, MbnA, to an oxazolon...
Alternative Titles
Full title
A mixed-valent Fe(II)Fe(III) species converts cysteine to an oxazolone/thioamide pair in methanobactin biosynthesis
Authors, Artists and Contributors
Author / Creator
Park, Yun Ji
Jodts, Richard J.
Slater, Jeffrey W.
Reyes, Reyvin M.
Winton, Valerie J.
Montaser, Rana A.
Thomas, Paul M.
Dowdle, William B.
Ruiz, Anahi
Kelleher, Neil L.
Bollinger, J. Martin
Krebs, Carsten
Hoffman, Brian M.
Rosenzweig, Amy C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9060507
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9060507
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.2123566119
