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Maladaptive myelination promotes generalized epilepsy progression

Maladaptive myelination promotes generalized epilepsy progression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9076538

Maladaptive myelination promotes generalized epilepsy progression

About this item

Full title

Maladaptive myelination promotes generalized epilepsy progression

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2022-05, Vol.25 (5), p.596-606

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Activity-dependent myelination can fine-tune neural network dynamics. Conversely, aberrant neuronal activity, as occurs in disorders of recurrent seizures (epilepsy), could promote maladaptive myelination, contributing to pathogenesis. In this study, we tested the hypothesis that activity-dependent myelination resulting from absence seizures, which...

Alternative Titles

Full title

Maladaptive myelination promotes generalized epilepsy progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9076538

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9076538

Other Identifiers

ISSN

1097-6256,1546-1726

E-ISSN

1546-1726

DOI

10.1038/s41593-022-01052-2

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