Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication
About this item
Full title
Author / Creator
Theruvath, Johanna , Menard, Marie , Smith, Benjamin A. H. , Linde, Miles H. , Coles, Garry L. , Dalton, Guillermo Nicolas , Wu, Wei , Kiru, Louise , Delaidelli, Alberto , Sotillo, Elena , Silberstein, John L. , Geraghty, Anna C. , Banuelos, Allison , Radosevich, Molly Thomas , Dhingra, Shaurya , Heitzeneder, Sabine , Tousley, Aidan , Lattin, John , Xu, Peng , Huang, Jing , Nasholm, Nicole , He, Andy , Kuo, Tracy C. , Sangalang, Emma R. B. , Pons, Jaume , Barkal, Amira , Brewer, Rachel E. , Marjon, Kristopher D. , Vilches-Moure, Jose G. , Marshall, Payton L. , Fernandes, Ricardo , Monje, Michelle , Cochran, Jennifer R. , Sorensen, Poul H. , Daldrup-Link, Heike E. , Weissman, Irving L. , Sage, Julien , Majeti, Ravindra , Bertozzi, Carolyn R. , Weiss, William A. , Mackall, Crystal L. and Majzner, Robbie G.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The disialoganglioside GD2 is overexpressed on several solid tumors, and monoclonal antibodies targeting GD2 have substantially improved outcomes for children with high-risk neuroblastoma. However, approximately 40% of patients with neuroblastoma still relapse, and anti-GD2 has not mediated significant clinical activity in any other GD2
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Alternative Titles
Full title
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication
Authors, Artists and Contributors
Author / Creator
Menard, Marie
Smith, Benjamin A. H.
Linde, Miles H.
Coles, Garry L.
Dalton, Guillermo Nicolas
Wu, Wei
Kiru, Louise
Delaidelli, Alberto
Sotillo, Elena
Silberstein, John L.
Geraghty, Anna C.
Banuelos, Allison
Radosevich, Molly Thomas
Dhingra, Shaurya
Heitzeneder, Sabine
Tousley, Aidan
Lattin, John
Xu, Peng
Huang, Jing
Nasholm, Nicole
He, Andy
Kuo, Tracy C.
Sangalang, Emma R. B.
Pons, Jaume
Barkal, Amira
Brewer, Rachel E.
Marjon, Kristopher D.
Vilches-Moure, Jose G.
Marshall, Payton L.
Fernandes, Ricardo
Monje, Michelle
Cochran, Jennifer R.
Sorensen, Poul H.
Daldrup-Link, Heike E.
Weissman, Irving L.
Sage, Julien
Majeti, Ravindra
Bertozzi, Carolyn R.
Weiss, William A.
Mackall, Crystal L.
Majzner, Robbie G.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9098186
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9098186
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-021-01625-x
