Zwitterionic Modification of Polyethyleneimine for Efficient In Vitro siRNA Delivery
Zwitterionic Modification of Polyethyleneimine for Efficient In Vitro siRNA Delivery
About this item
Full title
Author / Creator
Liu, Fengfan , Su, Huahui , Li, Mengqian , Xie, Wanxuan , Yan, Yunfeng and Shuai, Qi
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
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Scope and Contents
Contents
Polyethylenimine (PEI) has been widely used in gene delivery. However, its high cytotoxicity and undesired non-specific protein adsorption hinder the overall delivery efficacy and the practical applications of PEI-based gene delivery systems. In this study, we prepared hydrophobically modified PEIs (H-PEIs) via the reaction of octanal with 40% of p...
Alternative Titles
Full title
Zwitterionic Modification of Polyethyleneimine for Efficient In Vitro siRNA Delivery
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9100541
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9100541
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms23095014
