HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate ca...
HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
HOXB13, a homeodomain transcription factor, critically regulates androgen receptor (AR) activities and androgen-dependent prostate cancer (PCa) growth. However, its functions in AR-independent contexts remain elusive. Here we report HOXB13 interaction with histone deacetylase HDAC3, which is disrupted by the HOXB13 G84E mutation that has been assoc...
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Full title
HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9117466
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9117466
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-022-01045-8
