Relationship between astrocyte reactivity, using novel 11C-BU99008 PET, and glucose metabolism, grey...
Relationship between astrocyte reactivity, using novel 11C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals
About this item
Full title
Author / Creator
Livingston, Nicholas R. , Calsolaro, Valeria , Hinz, Rainer , Nowell, Joseph , Raza, Sanara , Gentleman, Steve , Tyacke, Robin J. , Myers, Jim , Venkataraman, Ashwin V. , Perneczky, Robert , Gunn, Roger N. , Rabiner, Eugenii A. , Parker, Christine A. , Murphy, Philip S. , Wren, Paul B. , Nutt, David J. , Matthews, Paul M. and Edison, Paul
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Post mortem
neuropathology suggests that astrocyte reactivity may play a significant role in neurodegeneration in Alzheimer’s disease. We explored this in vivo using multimodal PET and MRI imaging. Twenty subjects (11 older, cognitively impaired patients and 9 age-matched healthy controls) underwent brain scanning using the novel reactive astroc...
Alternative Titles
Full title
Relationship between astrocyte reactivity, using novel 11C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals
Authors, Artists and Contributors
Author / Creator
Calsolaro, Valeria
Hinz, Rainer
Nowell, Joseph
Raza, Sanara
Gentleman, Steve
Tyacke, Robin J.
Myers, Jim
Venkataraman, Ashwin V.
Perneczky, Robert
Gunn, Roger N.
Rabiner, Eugenii A.
Parker, Christine A.
Murphy, Philip S.
Wren, Paul B.
Nutt, David J.
Matthews, Paul M.
Edison, Paul
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9126819
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9126819
Other Identifiers
ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-021-01429-y
