Definition of the Prognostic Role of MGMT Promoter Methylation Value by Pyrosequencing in Newly Diag...
Definition of the Prognostic Role of MGMT Promoter Methylation Value by Pyrosequencing in Newly Diagnosed IDH Wild-Type Glioblastoma Patients Treated with Radiochemotherapy: A Large Multicenter Study
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Author / Creator
Caccese, Mario , Simonelli, Matteo , Villani, Veronica , Rizzato, Simona , Ius, Tamara , Pasqualetti, Francesco , Russo, Marco , Rudà, Roberta , Amoroso, Rosina , Bellu, Luisa , Bertorelle, Roberta , Cavallin, Francesco , Dipasquale, Angelo , Carosi, Mariantonia , Pizzolitto, Stefano , Cesselli, Daniela , Persico, Pasquale , Casini, Beatrice , Fassan, Matteo , Zagonel, Vittorina and Lombardi, Giuseppe
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Background. O6-methylguanine (O6-MeG)-DNA methyltransferase (MGMT) methylation status is a predictive factor for alkylating treatment efficacy in glioblastoma patients, but its prognostic role is still unclear. We performed a large, multicenter study to evaluate the association between MGMT methylation value and survival. Methods. We evaluated glio...
Alternative Titles
Full title
Definition of the Prognostic Role of MGMT Promoter Methylation Value by Pyrosequencing in Newly Diagnosed IDH Wild-Type Glioblastoma Patients Treated with Radiochemotherapy: A Large Multicenter Study
Authors, Artists and Contributors
Author / Creator
Simonelli, Matteo
Villani, Veronica
Rizzato, Simona
Ius, Tamara
Pasqualetti, Francesco
Russo, Marco
Rudà, Roberta
Amoroso, Rosina
Bellu, Luisa
Bertorelle, Roberta
Cavallin, Francesco
Dipasquale, Angelo
Carosi, Mariantonia
Pizzolitto, Stefano
Cesselli, Daniela
Persico, Pasquale
Casini, Beatrice
Fassan, Matteo
Zagonel, Vittorina
Lombardi, Giuseppe
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9139569
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9139569
Other Identifiers
ISSN
2072-6694
E-ISSN
2072-6694
DOI
10.3390/cancers14102425
