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Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9139966

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells

About this item

Full title

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells

Publisher

Switzerland: MDPI AG

Journal title

Cancers, 2022-05, Vol.14 (10), p.2508

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Transforming growth factor-β (TGF-β) signaling is tightly controlled in duration and intensity during embryonic development and in the adult to maintain tissue homeostasis. To visualize the TGF-β/SMAD3 signaling kinetics, we developed a dynamic TGF-β/SMAD3 transcriptional fluorescent reporter using multimerized SMAD3/4 binding elements driving the...

Alternative Titles

Full title

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9139966

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9139966

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers14102508

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