Log in to save to my catalogue

Why succinate? Physiological regulation by a mitochondrial coenzyme Q sentinel

Why succinate? Physiological regulation by a mitochondrial coenzyme Q sentinel

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9150600

Why succinate? Physiological regulation by a mitochondrial coenzyme Q sentinel

About this item

Full title

Why succinate? Physiological regulation by a mitochondrial coenzyme Q sentinel

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2022-05, Vol.18 (5), p.461-469

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Metabolites once considered solely in catabolism or anabolism turn out to have key regulatory functions. Among these, the citric acid cycle intermediate succinate stands out owing to its multiple roles in disparate pathways, its dramatic concentration changes and its selective cell release. Here we propose that succinate has evolved as a signaling...

Alternative Titles

Full title

Why succinate? Physiological regulation by a mitochondrial coenzyme Q sentinel

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9150600

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9150600

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-022-01004-8

How to access this item