Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1
Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1
About this item
Full title
Author / Creator
Tsou, Pei-Suen , Lu, Chenyang , Gurrea-Rubio, Mikel , Muraoka, Sei , Campbell, Phillip L. , Wu, Qi , Model, Ellen N. , Lind, Matthew E. , Vichaikul, Sirapa , Mattichak, Megan N. , Brodie, William D. , Hervoso, Jonatan L. , Ory, Sarah , Amarista, Camila I. , Pervez, Rida , Junginger, Lucas , Ali, Mustafa , Hodish, Gal , O’Mara, Morgan M. , Ruth, Jeffrey H. , Robida, Aaron M. , Alt, Andrew J. , Zhang, Chengxin , Urquhart, Andrew G. , Lawton, Jeffrey N. , Chung, Kevin C. , Maerz, Tristan , Saunders, Thomas L. , Groppi, Vincent E. , Fox, David A. and Amin, M. Asif
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
CD13, an ectoenzyme on myeloid and stromal cells, also circulates as a shed, soluble protein (sCD13) with powerful chemoattractant, angiogenic, and arthritogenic properties, which require engagement of a G protein-coupled receptor (GPCR). Here we identify the GPCR that mediates sCD13 arthritogenic actions as the bradykinin receptor B1 (B1R). Immuno...
Alternative Titles
Full title
Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1
Authors, Artists and Contributors
Author / Creator
Lu, Chenyang
Gurrea-Rubio, Mikel
Muraoka, Sei
Campbell, Phillip L.
Wu, Qi
Model, Ellen N.
Lind, Matthew E.
Vichaikul, Sirapa
Mattichak, Megan N.
Brodie, William D.
Hervoso, Jonatan L.
Ory, Sarah
Amarista, Camila I.
Pervez, Rida
Junginger, Lucas
Ali, Mustafa
Hodish, Gal
O’Mara, Morgan M.
Ruth, Jeffrey H.
Robida, Aaron M.
Alt, Andrew J.
Zhang, Chengxin
Urquhart, Andrew G.
Lawton, Jeffrey N.
Chung, Kevin C.
Maerz, Tristan
Saunders, Thomas L.
Groppi, Vincent E.
Fox, David A.
Amin, M. Asif
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9151693
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9151693
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI151827
