α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody–positive ind...
α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody–positive individuals
About this item
Full title
Author / Creator
Doliba, Nicolai M. , Rozo, Andrea V. , Roman, Jeffrey , Qin, Wei , Traum, Daniel , Gao, Long , Liu, Jinping , Manduchi, Elisabetta , Liu, Chengyang , Golson, Maria L. , Vahedi, Golnaz , Naji, Ali , Matschinsky, Franz M. , Atkinson, Mark A. , Powers, Alvin C. , Brissova, Marcela , Kaestner, Klaus H. , Stoffers, Doris A. and HPAP Consortium
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
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More information
Scope and Contents
Contents
BACKGROUNDMultiple islet autoantibodies (AAbs) predict the development of type 1 diabetes (T1D) and hyperglycemia within 10 years. By contrast, T1D develops in only approximately 15% of individuals who are positive for single AAbs (generally against glutamic acid decarboxylase [GADA]); hence, the single GADA+ state may represent an early stage of T...
Alternative Titles
Full title
α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody–positive individuals
Authors, Artists and Contributors
Author / Creator
Rozo, Andrea V.
Roman, Jeffrey
Qin, Wei
Traum, Daniel
Gao, Long
Liu, Jinping
Manduchi, Elisabetta
Liu, Chengyang
Golson, Maria L.
Vahedi, Golnaz
Naji, Ali
Matschinsky, Franz M.
Atkinson, Mark A.
Powers, Alvin C.
Brissova, Marcela
Kaestner, Klaus H.
Stoffers, Doris A.
HPAP Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9151702
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9151702
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI156243