Genome-wide enhancer maps link risk variants to disease genes
Genome-wide enhancer maps link risk variants to disease genes
About this item
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Author / Creator
Nasser, Joseph , Bergman, Drew T. , Fulco, Charles P. , Guckelberger, Philine , Doughty, Benjamin R. , Patwardhan, Tejal A. , Jones, Thouis R. , Nguyen, Tung H. , Ulirsch, Jacob C. , Lekschas, Fritz , Mualim, Kristy , Natri, Heini M. , Weeks, Elle M. , Munson, Glen , Kane, Michael , Kang, Helen Y. , Cui, Ang , Ray, John P. , Eisenhaure, Thomas M. , Collins, Ryan L. , Dey, Kushal , Pfister, Hanspeter , Price, Alkes L. , Epstein, Charles B. , Kundaje, Anshul , Xavier, Ramnik J. , Daly, Mark J. , Huang, Hailiang , Finucane, Hilary K. , Hacohen, Nir , Lander, Eric S. and Engreitz, Jesse M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Genome-wide association studies (GWAS) have identified thousands of noncoding loci that are associated with human diseases and complex traits, each of which could reveal insights into the mechanisms of disease
1
. Many of the underlying causal variants may affect enhancers
2
,
3
, but we lack accurate maps of enhancers and their t...
Alternative Titles
Full title
Genome-wide enhancer maps link risk variants to disease genes
Authors, Artists and Contributors
Author / Creator
Bergman, Drew T.
Fulco, Charles P.
Guckelberger, Philine
Doughty, Benjamin R.
Patwardhan, Tejal A.
Jones, Thouis R.
Nguyen, Tung H.
Ulirsch, Jacob C.
Lekschas, Fritz
Mualim, Kristy
Natri, Heini M.
Weeks, Elle M.
Munson, Glen
Kane, Michael
Kang, Helen Y.
Cui, Ang
Ray, John P.
Eisenhaure, Thomas M.
Collins, Ryan L.
Dey, Kushal
Pfister, Hanspeter
Price, Alkes L.
Epstein, Charles B.
Kundaje, Anshul
Xavier, Ramnik J.
Daly, Mark J.
Huang, Hailiang
Finucane, Hilary K.
Hacohen, Nir
Lander, Eric S.
Engreitz, Jesse M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9153265
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9153265
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03446-x
