Defined tumor antigen-specific T cells potentiate personalized TCR-T cell therapy and prediction of...
Defined tumor antigen-specific T cells potentiate personalized TCR-T cell therapy and prediction of immunotherapy response
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Author / Creator
He, Jingjing , Xiong, Xinxin , Yang, Han , Li, Dandan , Liu, Xuefei , Li, Shuo , Liao, Shuangye , Chen, Siyu , Wen, Xizhi , Yu, Kuai , Fu, Lingyi , Dong, Xingjun , Zhu, Kaiyu , Xia, Xiaojun , Kang, Tiebang , Bian, Chaochao , Li, Xiang , Liu, Haiping , Ding, Peirong , Zhang, Xiaoshi , Liu, Zhenjiang , Li, Wende , Zuo, Zhixiang and Zhou, Penghui
Publisher
Singapore: Springer Nature Singapore
Journal title
Language
English
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Publisher
Singapore: Springer Nature Singapore
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Scope and Contents
Contents
Personalized immunotherapy targeting tumor-specific antigens (TSAs) could generate efficient and safe antitumor immune response without damaging normal tissues. Although neoantigen vaccines have shown therapeutic effect in clinic trials, precise prediction of neoantigens from tumor mutations is still challenging. The host antitumor immune response...
Alternative Titles
Full title
Defined tumor antigen-specific T cells potentiate personalized TCR-T cell therapy and prediction of immunotherapy response
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Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9160085
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9160085
Other Identifiers
ISSN
1748-7838,1001-0602
E-ISSN
1748-7838
DOI
10.1038/s41422-022-00627-9
