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Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ve...

Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ve...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9170191

Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation

About this item

Full title

Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation

Publisher

Athens: Spandidos Publications UK Ltd

Journal title

International journal of molecular medicine, 2022-07, Vol.50 (1), Article 96

Language

English

Formats

Publication information

Publisher

Athens: Spandidos Publications UK Ltd

More information

Scope and Contents

Contents

Alveolar macrophages (AMs) play an essential role in ventilator-induced lung injury (VILI). Exosomes and their cargo, including microRNAs (miRNAs/miRs) serve as regulators of the intercellular communications between macrophages and epithelial cells (ECs), and are involved in maintaining homeostasis in lung tissue. The present study found that exoso...

Alternative Titles

Full title

Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9170191

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9170191

Other Identifiers

ISSN

1107-3756

E-ISSN

1791-244X

DOI

10.3892/ijmm.2022.5152

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