Biomarkers of response to PD-1 pathway blockade
Biomarkers of response to PD-1 pathway blockade
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The binding of T cell immune checkpoint proteins programmed death 1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) to their ligands allows immune evasion by tumours. The development of therapeutic antibodies, termed checkpoint inhibitors, that bind these molecules or their ligands, has provided a means to release this brake on the...
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Full title
Biomarkers of response to PD-1 pathway blockade
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9174485
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9174485
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-022-01743-4