Notch1/Hes1‑PTEN/AKT/IL‑17A feedback loop regulates Th17 cell differentiation in mouse psoriasis‑lik...
Notch1/Hes1‑PTEN/AKT/IL‑17A feedback loop regulates Th17 cell differentiation in mouse psoriasis‑like skin inflammation
About this item
Full title
Author / Creator
Lin, Ya-Wen , Li, Xin-Xin , Fu, Fang-Hui , Liu, Bin , Xing, Xiaoyun , Qi, Ruiqun and Ma, Lei
Publisher
Greece: Spandidos Publications
Journal title
Language
English
Formats
Publication information
Publisher
Greece: Spandidos Publications
Subjects
More information
Scope and Contents
Contents
IL‑17A, the effector cytokine of T helper (Th) 17 cells, plays a crucial role in the pathogenesis of psoriasis. The Notch1 and PI3K/AKT signaling pathways are implicated in Th17 cell differentiation and IL‑17A production. The present study aimed to evaluate the regulatory effect of the Notch1/hairy and enhancer of split 1 (Hes1)‑PTEN/AKT/IL‑17A fee...
Alternative Titles
Full title
Notch1/Hes1‑PTEN/AKT/IL‑17A feedback loop regulates Th17 cell differentiation in mouse psoriasis‑like skin inflammation
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9175275
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9175275
Other Identifiers
ISSN
1791-2997
E-ISSN
1791-3004
DOI
10.3892/mmr.2022.12739
