Immune-Desert Tumor Microenvironment in Thoracic SMARCA4-Deficient Undifferentiated Tumors with Limi...
Immune-Desert Tumor Microenvironment in Thoracic SMARCA4-Deficient Undifferentiated Tumors with Limited Efficacy of Immune Checkpoint Inhibitors
About this item
Full title
Author / Creator
Gantzer, Justine , Davidson, Guillaume , Vokshi, Bujamin , Weingertner, Noëlle , Bougoüin, Antoine , Moreira, Marco , Lindner, Véronique , Lacroix, Guillaume , Mascaux, Céline , Chenard, Marie-Pierre , Bertucci, François , Davidson, Irwin , Kurtz, Jean-Emmanuel , Sautès-Fridman, Catherine , Fridman, Wolf H and Malouf, Gabriel G
Publisher
US: Oxford University Press
Journal title
Language
English
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Publication information
Publisher
US: Oxford University Press
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Scope and Contents
Contents
Abstract
Background
Thoracic SMARCA4-deficient undifferentiated tumors (SMARCA4-UT) are aggressive neoplasms. Data linking BAF alterations with tumor microenvironment (TME) and efficacy of immune checkpoint inhibitors (ICI) are contradictory. The TME of SMARCA4-UT and their response to ICI are unknown.
Materials and Methods
Patients dia...
Alternative Titles
Full title
Immune-Desert Tumor Microenvironment in Thoracic SMARCA4-Deficient Undifferentiated Tumors with Limited Efficacy of Immune Checkpoint Inhibitors
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9177113
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9177113
Other Identifiers
ISSN
1083-7159
E-ISSN
1549-490X
DOI
10.1093/oncolo/oyac040