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Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis

Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9177596

Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis

About this item

Full title

Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis

Publisher

London: Nature Publishing Group UK

Journal title

Cell death and differentiation, 2022-06, Vol.29 (6), p.1187-1198

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Amyotrophic lateral sclerosis (ALS) is caused by selective degeneration of motor neurons in the brain and spinal cord; however, the primary cell death pathway(s) mediating motor neuron demise remain elusive. We recently established that necroptosis, an inflammatory form of regulated cell death, was dispensable for motor neuron death in a mouse mode...

Alternative Titles

Full title

Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9177596

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9177596

Other Identifiers

ISSN

1350-9047

E-ISSN

1476-5403

DOI

10.1038/s41418-021-00910-z

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