Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis
Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Amyotrophic lateral sclerosis (ALS) is caused by selective degeneration of motor neurons in the brain and spinal cord; however, the primary cell death pathway(s) mediating motor neuron demise remain elusive. We recently established that necroptosis, an inflammatory form of regulated cell death, was dispensable for motor neuron death in a mouse mode...
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Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9177596
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9177596
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/s41418-021-00910-z