Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3
Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Impaired chronic viral and tumor clearance has been attributed to CD8
+
T cell exhaustion, a differentiation state in which T cells have reduced and altered effector function that can be partially reversed upon blockade of inhibitory receptors. The role of the exhaustion program and transcriptional networks that control CD8
+
T cell fun...
Alternative Titles
Full title
Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9179227
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9179227
Other Identifiers
ISSN
1529-2908,1529-2916
E-ISSN
1529-2916
DOI
10.1038/s41590-022-01210-5
