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Effect of Acrylamide Treatment on Cyp2e1 Expression and Redox Status in Rat Hepatocytes

Effect of Acrylamide Treatment on Cyp2e1 Expression and Redox Status in Rat Hepatocytes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9181519

Effect of Acrylamide Treatment on Cyp2e1 Expression and Redox Status in Rat Hepatocytes

About this item

Full title

Effect of Acrylamide Treatment on Cyp2e1 Expression and Redox Status in Rat Hepatocytes

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2022-05, Vol.23 (11), p.6062

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Acrylamide (AA) toxicity is associated with oxidative stress. During detoxification, AA is either coupled to gluthatione or biotransformed to glycidamide by the enzyme cytochrome P450 2E1 (CYP2E1). The aim of our study was to examine the hepatotoxicity of AA in vivo and in vitro. Thirty male Wistar rats were treated with 25 or 50 mg/kg b.w. of AA f...

Alternative Titles

Full title

Effect of Acrylamide Treatment on Cyp2e1 Expression and Redox Status in Rat Hepatocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9181519

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9181519

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms23116062

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