Effect of AZD4017, a Selective 11β-HSD1 Inhibitor, on Bone Turnover Markers in Postmenopausal Osteop...
Effect of AZD4017, a Selective 11β-HSD1 Inhibitor, on Bone Turnover Markers in Postmenopausal Osteopenia
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United States: Oxford University Press
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Language
English
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United States: Oxford University Press
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The causative link between circulating glucocorticoid excess and osteoporosis is well-established. The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which increases local cortisol production, is expressed in human osteoblasts and its activity increases with age.
We hypothesized that local 11β-HSD1 might mediate an age-related decrea...
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Full title
Effect of AZD4017, a Selective 11β-HSD1 Inhibitor, on Bone Turnover Markers in Postmenopausal Osteopenia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9202729
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9202729
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ISSN
0021-972X
E-ISSN
1945-7197
DOI
10.1210/clinem/dgac100
