Claudin18.2-specific CAR T cells in gastrointestinal cancers: phase 1 trial interim results
Claudin18.2-specific CAR T cells in gastrointestinal cancers: phase 1 trial interim results
About this item
Full title
Author / Creator
Qi, Changsong , Gong, Jifang , Li, Jian , Liu, Dan , Qin, Yanru , Ge, Sai , Zhang, Miao , Peng, Zhi , Zhou, Jun , Cao, Yanshuo , Zhang, Xiaotian , Lu, Zhihao , Lu, Ming , Yuan, Jiajia , Wang, Zhenghang , Wang, Yakun , Peng, Xiaohui , Gao, Huiping , Liu, Zhen , Wang, Huamao , Yuan, Daijing , Xiao, Jun , Ma, Hong , Wang, Wei , Li, Zonghai and Shen, Lin
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Despite success in hematologic malignancies, the treatment landscape of chimeric antigen receptor (CAR) T cell therapy for solid tumors remains limited. Claudin18.2 (CLDN18.2)-redirected CAR T cells showed promising efficacy against gastric cancer (GC) in a preclinical study. Here we report the interim analysis results of an ongoing, open-label, si...
Alternative Titles
Full title
Claudin18.2-specific CAR T cells in gastrointestinal cancers: phase 1 trial interim results
Authors, Artists and Contributors
Author / Creator
Gong, Jifang
Li, Jian
Liu, Dan
Qin, Yanru
Ge, Sai
Zhang, Miao
Peng, Zhi
Zhou, Jun
Cao, Yanshuo
Zhang, Xiaotian
Lu, Zhihao
Lu, Ming
Yuan, Jiajia
Wang, Zhenghang
Wang, Yakun
Peng, Xiaohui
Gao, Huiping
Liu, Zhen
Wang, Huamao
Yuan, Daijing
Xiao, Jun
Ma, Hong
Wang, Wei
Li, Zonghai
Shen, Lin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9205778
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9205778
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-022-01800-8
