Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical...
Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial
About this item
Full title
Author / Creator
Padrón, Lacey J. , Maurer, Deena M. , O’Hara, Mark H. , O’Reilly, Eileen M. , Wolff, Robert A. , Wainberg, Zev A. , Ko, Andrew H. , Fisher, George , Rahma, Osama , Lyman, Jaclyn P. , Cabanski, Christopher R. , Yu, Jia Xin , Pfeiffer, Shannon M. , Spasic, Marko , Xu, Jingying , Gherardini, Pier Federico , Karakunnel, Joyson , Mick, Rosemarie , Alanio, Cécile , Byrne, Katelyn T. , Hollmann, Travis J. , Moore, Jonni S. , Jones, Derek D. , Tognetti, Marco , Chen, Richard O. , Yang, Xiaodong , Salvador, Lisa , Wherry, E. John , Dugan, Ute , O’Donnell-Tormey, Jill , Butterfield, Lisa H. , Hubbard-Lucey, Vanessa M. , Ibrahim, Ramy , Fairchild, Justin , Bucktrout, Samantha , LaVallee, Theresa M. and Vonderheide, Robert H.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Chemotherapy combined with immunotherapy has improved the treatment of certain solid tumors, but effective regimens remain elusive for pancreatic ductal adenocarcinoma (PDAC). We conducted a randomized phase 2 trial evaluating the efficacy of nivolumab (nivo; anti-PD-1) and/or sotigalimab (sotiga; CD40 agonistic antibody) with gemcitabine/nab-pacli...
Alternative Titles
Full title
Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial
Authors, Artists and Contributors
Author / Creator
Maurer, Deena M.
O’Hara, Mark H.
O’Reilly, Eileen M.
Wolff, Robert A.
Wainberg, Zev A.
Ko, Andrew H.
Fisher, George
Rahma, Osama
Lyman, Jaclyn P.
Cabanski, Christopher R.
Yu, Jia Xin
Pfeiffer, Shannon M.
Spasic, Marko
Xu, Jingying
Gherardini, Pier Federico
Karakunnel, Joyson
Mick, Rosemarie
Alanio, Cécile
Byrne, Katelyn T.
Hollmann, Travis J.
Moore, Jonni S.
Jones, Derek D.
Tognetti, Marco
Chen, Richard O.
Yang, Xiaodong
Salvador, Lisa
Wherry, E. John
Dugan, Ute
O’Donnell-Tormey, Jill
Butterfield, Lisa H.
Hubbard-Lucey, Vanessa M.
Ibrahim, Ramy
Fairchild, Justin
Bucktrout, Samantha
LaVallee, Theresa M.
Vonderheide, Robert H.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9205784
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9205784
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-022-01829-9
