IFN-γ+ cytotoxic CD4+ T lymphocytes are involved in the pathogenesis of colitis induced by IL-23 and...
IFN-γ+ cytotoxic CD4+ T lymphocytes are involved in the pathogenesis of colitis induced by IL-23 and the food colorant Red 40
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The food colorant Red 40 is an environmental risk factor for colitis development in mice with increased expression of interleukin (IL)-23. This immune response is mediated by CD4
+
T cells, but mechanistic insights into how these CD4
+
T cells trigger and perpetuate colitis have remained elusive. Here, using single-cell transcriptomic a...
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Full title
IFN-γ+ cytotoxic CD4+ T lymphocytes are involved in the pathogenesis of colitis induced by IL-23 and the food colorant Red 40
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9243055
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9243055
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ISSN
2042-0226,1672-7681
E-ISSN
2042-0226
DOI
10.1038/s41423-022-00864-3
