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Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped Wit...

Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped Wit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9246774

Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells

About this item

Full title

Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells

Publisher

New York: Springer US

Journal title

Pharmaceutical research, 2022-07, Vol.39 (7), p.1535-1547

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Purpose
The purpose of this study was to construct and validate an
in vitro
 three-dimensional blood–brain barrier (3DBBB) model system equipped with brain microvascular endothelial cells derived from human induced pluripotent stem cells (hiPS-BMECs).
Methods
The 3D-BBB system was constructed by seeding hiPS-BMECs onto the capillary...

Alternative Titles

Full title

Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9246774

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9246774

Other Identifiers

ISSN

0724-8741

E-ISSN

1573-904X

DOI

10.1007/s11095-022-03249-3

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