Addiction of Merkel cell carcinoma to MUC1-C identifies a potential new target for treatment
Addiction of Merkel cell carcinoma to MUC1-C identifies a potential new target for treatment
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Merkel cell carcinoma (MCC) is an aggressive malignancy with neuroendocrine (NE) features, limited treatment options, and a lack of druggable targets. There is no reported involvement of the MUC1-C oncogenic protein in MCC progression. We show here that MUC1-C is broadly expressed in MCCs and at higher levels in Merkel cell polyomavirus (MCPyV)-pos...
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Addiction of Merkel cell carcinoma to MUC1-C identifies a potential new target for treatment
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9249628
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9249628
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-022-02361-3
