Mechanisms of 8‐aminoquinoline induced haemolytic toxicity in a G6PDd humanized mouse model
Mechanisms of 8‐aminoquinoline induced haemolytic toxicity in a G6PDd humanized mouse model
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Publisher
England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Contents
Primaquine (PQ) and Tafenoquine (TQ) are clinically important 8‐aminoquinolines (8‐AQ) used for radical cure treatment of P. vivax infection, known to target hepatic hypnozoites. 8‐AQs can trigger haemolytic anaemia in individuals with glucose‐6‐phosphate dehydrogenase deficiency (G6PDd), yet the mechanisms of haemolytic toxicity remain unknown. To...
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Full title
Mechanisms of 8‐aminoquinoline induced haemolytic toxicity in a G6PDd humanized mouse model
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9258708
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9258708
Other Identifiers
ISSN
1582-1838
E-ISSN
1582-4934
DOI
10.1111/jcmm.17362
