Clinical Utility of Liquid Biopsy to Detect BRAF and NRAS Mutations in Stage III/IV Melanoma Patient...
Clinical Utility of Liquid Biopsy to Detect BRAF and NRAS Mutations in Stage III/IV Melanoma Patients by Using Real-Time PCR
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Author / Creator
Giunta, Emilio Francesco , De Falco, Vincenzo , Vitiello, Pietro Paolo , Guerrera, Luigi Pio , Suarato, Gabriella , Napolitano, Rossella , Perrone, Alessandra , Argenziano, Giuseppe , Franco, Renato , Caraglia, Michele , Martinelli, Erika , Ciardiello, Davide , Ciardiello, Fortunato , Napolitano, Stefania and Troiani, Teresa
Publisher
Basel: MDPI AG
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Language
English
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Publisher
Basel: MDPI AG
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Contents
Background: Liquid biopsy is a potentially useful tool for melanoma patients, also for detecting BRAS/NRAS mutations, even if the tissue analysis remains the current standard. Methods: In this work, we tested ctDNA on plasma samples from 56 BRAF-V600/NRAS mutant stage III/IV melanoma patients using a real-time quantitative PCR (qPCR)-based platform...
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Full title
Clinical Utility of Liquid Biopsy to Detect BRAF and NRAS Mutations in Stage III/IV Melanoma Patients by Using Real-Time PCR
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9265107
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9265107
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ISSN
2072-6694
E-ISSN
2072-6694
DOI
10.3390/cancers14133053