Metal-free domino amination-Knoevenagel condensation approach to access new coumarins as potent nano...
Metal-free domino amination-Knoevenagel condensation approach to access new coumarins as potent nanomolar inhibitors of VEGFR-2 and EGFR
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Publisher
Abingdon: Taylor & Francis
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Language
English
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Publisher
Abingdon: Taylor & Francis
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Contents
A metal-free, atom-economy and simple work-up domino amination-Knoevenagel condensation approach to construct new coumarin analogous (4a-f and 8a-e) was described. Further, new formyl (5a,d-f) and nitro (9a,d-f) coumarin derivatives were synthesized via C-N coupling reaction of various cyclic secondary amines and 4-chloro-3-(formyl-/nitro)coumarins...
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Full title
Metal-free domino amination-Knoevenagel condensation approach to access new coumarins as potent nanomolar inhibitors of VEGFR-2 and EGFR
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9273165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9273165
Other Identifiers
ISSN
1751-8253
E-ISSN
1751-7192
DOI
10.1080/17518253.2021.1981462