Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer
Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer
About this item
Full title
Author / Creator
Revia, Steffie , Seretny, Agnieszka , Wendler, Lena , Banito, Ana , Eckert, Christoph , Breuer, Kersten , Mayakonda, Anand , Lutsik, Pavlo , Evert, Matthias , Ribback, Silvia , Gallage, Suchira , Chikh Bakri, Ismaiel , Breuhahn, Kai , Schirmacher, Peter , Heinrich, Stefan , Gaida, Matthias M , Heikenwälder, Mathias , Calvisi, Diego F , Plass, Christoph , Lowe, Scott W and Tschaharganeh, Darjus F
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Subjects
More information
Scope and Contents
Contents
ObjectiveLarge-scale genome sequencing efforts of human tumours identified epigenetic modifiers as one of the most frequently mutated gene class in human cancer. However, how these mutations drive tumour development and tumour progression are largely unknown. Here, we investigated the function of the histone demethylase KDM6A in gastrointestinal ca...
Alternative Titles
Full title
Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer
Authors, Artists and Contributors
Author / Creator
Seretny, Agnieszka
Wendler, Lena
Banito, Ana
Eckert, Christoph
Breuer, Kersten
Mayakonda, Anand
Lutsik, Pavlo
Evert, Matthias
Ribback, Silvia
Gallage, Suchira
Chikh Bakri, Ismaiel
Breuhahn, Kai
Schirmacher, Peter
Heinrich, Stefan
Gaida, Matthias M
Heikenwälder, Mathias
Calvisi, Diego F
Plass, Christoph
Lowe, Scott W
Tschaharganeh, Darjus F
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9279849
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9279849
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2021-325405
