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Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy

Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9282839

Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy

About this item

Full title

Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy

Publisher

England: John Wiley & Sons, Inc

Journal title

Aging cell, 2022-07, Vol.21 (7), p.e13615-n/a

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Intracellular accumulation of filamentous tau aggregates with progressive neuronal loss is a common characteristic of tauopathies. Although the neurodegenerative mechanism of tau‐associated pathology remains unclear, molecular elements capable of degrading and/or sequestering neurotoxic tau species may suppress neurodegenerative progression. Here,...

Alternative Titles

Full title

Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9282839

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9282839

Other Identifiers

ISSN

1474-9718

E-ISSN

1474-9726

DOI

10.1111/acel.13615

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