Fate‐mapping of erythropoietin‐producing cells in mouse models of hypoxaemia and renal tissue remode...
Fate‐mapping of erythropoietin‐producing cells in mouse models of hypoxaemia and renal tissue remodelling reveals repeated recruitment and persistent functionality
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Publisher
England: Wiley Subscription Services, Inc
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Language
English
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Publisher
England: Wiley Subscription Services, Inc
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Aim
Fibroblast‐like renal erythropoietin (Epo) producing (REP) cells of the corticomedullary border region “sense” a decrease in blood oxygen content following anaemia or hypoxaemia. Burst‐like transcription of Epo during tissue hypoxia is transient and is lost during fibrotic tissue remodelling, as observed in chronic kidney disease. The reason...
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Full title
Fate‐mapping of erythropoietin‐producing cells in mouse models of hypoxaemia and renal tissue remodelling reveals repeated recruitment and persistent functionality
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9286872
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9286872
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ISSN
1748-1708
E-ISSN
1748-1716
DOI
10.1111/apha.13768
