Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail...
Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail Differently
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Switzerland: Springer Nature B.V
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Language
English
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Switzerland: Springer Nature B.V
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Activities of hepatic cytochrome P450 enzymes (CYPs) are relevant for hepatic clearance of drugs and known to be decreased in patients with liver cirrhosis. Several studies have reported the effect of liver cirrhosis on CYP activity, but the results are partially conflicting and for some CYPs lacking.
In this study, we aimed to investigate the C...
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Full title
Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail Differently
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9287224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9287224
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ISSN
0312-5963,1179-1926
E-ISSN
1179-1926
DOI
10.1007/s40262-022-01119-0
