Mitochondrial RNA modifications shape metabolic plasticity in metastasis
Mitochondrial RNA modifications shape metabolic plasticity in metastasis
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Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Aggressive and metastatic cancers show enhanced metabolic plasticity
1
, but the precise underlying mechanisms of this remain unclear. Here we show how two NOP2/Sun RNA methyltransferase 3 (NSUN3)-dependent RNA modifications—5-methylcytosine (m
5
C) and its derivative 5-formylcytosine (f
5
C) (refs.
2
–
4
)—drive the t...
Alternative Titles
Full title
Mitochondrial RNA modifications shape metabolic plasticity in metastasis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9300468
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9300468
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04898-5
