Poly(ADP-ribose) Polymerase 1 Mediates Rab5 Inactivation after DNA Damage
Poly(ADP-ribose) Polymerase 1 Mediates Rab5 Inactivation after DNA Damage
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Publisher
Basel: MDPI AG
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Language
English
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Basel: MDPI AG
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Contents
Parthanatos is programmed cell death mediated by poly(ADP-ribose) polymerase 1 (PARP1) after DNA damage. PARP1 acts by catalyzing the transfer of poly(ADP-ribose) (PAR) polymers to various nuclear proteins. PAR is subsequently cleaved, generating protein-free PAR polymers, which are translocated to the cytoplasm where they associate with cytoplasmi...
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Full title
Poly(ADP-ribose) Polymerase 1 Mediates Rab5 Inactivation after DNA Damage
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9319841
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9319841
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms23147827
