Neutrophil extracellular trap inhibition improves survival in neonatal mouse infectious peritonitis
Neutrophil extracellular trap inhibition improves survival in neonatal mouse infectious peritonitis
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Background
Treatment of neonatal peritonitis and sepsis is challenging. Following infection, neutrophils elaborate neutrophil extracellular traps (NETs)—extracellular lattices of decondensed chromatin decorated with antimicrobial proteins. NETs, however, can augment pathogenic inflammation causing collateral damage. We hypothesized that NET inhi...
Alternative Titles
Full title
Neutrophil extracellular trap inhibition improves survival in neonatal mouse infectious peritonitis
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9331023
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9331023
Other Identifiers
ISSN
0031-3998,1530-0447
E-ISSN
1530-0447
DOI
10.1038/s41390-022-02219-0
