PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a r...
PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer’s disease
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Author / Creator
Wang, Xiao-juan , Qi, Lin , Cheng, Ya-fang , Ji, Xue-fei , Chi, Tian-yan , Liu, Peng and Zou, Li-bo
Publisher
Singapore: Springer Nature Singapore
Journal title
Language
English
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Publisher
Singapore: Springer Nature Singapore
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Contents
PTEN-induced putative kinase 1 (PINK1)/parkin pathway mediates mitophagy, which is a specialized form of autophagy. Evidence shows that PINK1 can exert protective effects against stress-induced neuronal cell death. In the present study we investigated the effects of PINK1 overexpression on tau hyperphosphorylation, mitochondrial dysfunction and oxi...
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Full title
PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer’s disease
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Author / Creator
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9343460
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9343460
Other Identifiers
ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1038/s41401-021-00810-5
