Celsr3 Inactivation in the Brainstem Impairs Rubrospinal Tract Development and Mouse Behaviors in Mo...
Celsr3 Inactivation in the Brainstem Impairs Rubrospinal Tract Development and Mouse Behaviors in Motor Coordination and Mechanic-Induced Response
About this item
Full title
Author / Creator
Chen, Boli , Li, Fuxiang , Jia, Bin , So, Kwok-Fai , Wei, Ji-An , Liu, Yuchu , Qu, Yibo and Zhou, Libing
Publisher
New York: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer US
Subjects
More information
Scope and Contents
Contents
Inactivation of
Celsr3
in the forebrain results in defects of longitudinal axonal tracts such as the corticospinal tract. In this study, we inactivated
Celsr3
in the brainstem using En1-Cre mice (
Celsr3
cKO) and analyzed axonal and behavioral phenotypes.
Celsr3
cKO animals showed an 83% reduction of rubrospinal axons and 30...
Alternative Titles
Full title
Celsr3 Inactivation in the Brainstem Impairs Rubrospinal Tract Development and Mouse Behaviors in Motor Coordination and Mechanic-Induced Response
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9363480
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9363480
Other Identifiers
ISSN
0893-7648
E-ISSN
1559-1182
DOI
10.1007/s12035-022-02910-7
