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Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype

Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9369419

Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype

About this item

Full title

Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2022-08, Vol.23 (15), p.8797

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Kainate receptors belong to the family of glutamate receptors ion channels, which are responsible for the majority of rapid excitatory synaptic transmission in the central nervous system. The therapeutic potential of kainate receptors is still poorly understood, which is also due to the lack of potent and subunit-selective pharmacological tools. In...

Alternative Titles

Full title

Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9369419

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9369419

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms23158797

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