A programmable encapsulation system improves delivery of therapeutic bacteria in mice
A programmable encapsulation system improves delivery of therapeutic bacteria in mice
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Living bacteria therapies have been proposed as an alternative approach to treating a broad array of cancers. In this study, we developed a genetically encoded microbial encapsulation system with tunable and dynamic expression of surface capsular polysaccharides that enhances systemic delivery. Based on a small RNA screen of capsular biosynthesis p...
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Full title
A programmable encapsulation system improves delivery of therapeutic bacteria in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9371971
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9371971
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-022-01244-y
