Unique and joint associations of polygenic risk for major depression and opioid use disorder with en...
Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function
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Publisher
England: Nature Publishing Group
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Language
English
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Publisher
England: Nature Publishing Group
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Contents
Major depressive disorder (MDD) and opioid use disorder (OUD) are common, potentially fatal, polygenic disorders that are moderately heritable and often co-occur. We examined the unique and shared associations of polygenic risk scores (PRS) for these disorders with µ-opioid receptor (MOR) concentration and endogenous opioid response during a stress...
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Full title
Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9372136
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9372136
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ISSN
0893-133X,1740-634X
E-ISSN
1740-634X
DOI
10.1038/s41386-022-01325-1
