Improving antibody thermostability based on statistical analysis of sequence and structural consensu...
Improving antibody thermostability based on statistical analysis of sequence and structural consensus data
About this item
Full title
Author / Creator
Jia, Lei , Jain, Mani and Sun, Yaxiong
Publisher
Oxford: Oxford University Press
Journal title
Language
English
Formats
Publication information
Publisher
Oxford: Oxford University Press
Subjects
More information
Scope and Contents
Contents
Abstract
Background
The use of Monoclonal Antibodies (MAbs) as therapeutics has been increasing over the past 30 years due to their high specificity and strong affinity toward the target. One of the major challenges toward their use as drugs is their low thermostability, which impacts both efficacy as well as manufacturing and delivery.
Me...
Alternative Titles
Full title
Improving antibody thermostability based on statistical analysis of sequence and structural consensus data
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9372885
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9372885
Other Identifiers
ISSN
2516-4236
E-ISSN
2516-4236
DOI
10.1093/abt/tbac017
