Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected agai...
Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia
About this item
Full title
Author / Creator
Sepulveda-Falla, Diego , Sanchez, Justin S. , Almeida, Maria Camila , Boassa, Daniela , Acosta-Uribe, Juliana , Vila-Castelar, Clara , Ramirez-Gomez, Liliana , Baena, Ana , Aguillon, David , Villalba-Moreno, Nelson David , Littau, Jessica Lisa , Villegas, Andres , Beach, Thomas G. , White, Charles L. , Ellisman, Mark , Krasemann, Susanne , Glatzel, Markus , Johnson, Keith A. , Sperling, Reisa A. , Reiman, Eric M. , Arboleda-Velasquez, Joseph F. , Kosik, Kenneth S. , Lopera, Francisco and Quiroz, Yakeel T.
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
We describe in vivo follow-up PET imaging and postmortem findings from an autosomal dominant Alzheimer’s disease (ADAD)
PSEN1
E280A carrier who was also homozygous for the
APOE3
Christchurch (APOE3ch) variant and was protected against Alzheimer’s symptoms for almost three decades beyond the expected age of onset. We identified a distinc...
Alternative Titles
Full title
Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia
Authors, Artists and Contributors
Author / Creator
Sanchez, Justin S.
Almeida, Maria Camila
Boassa, Daniela
Acosta-Uribe, Juliana
Vila-Castelar, Clara
Ramirez-Gomez, Liliana
Baena, Ana
Aguillon, David
Villalba-Moreno, Nelson David
Littau, Jessica Lisa
Villegas, Andres
Beach, Thomas G.
White, Charles L.
Ellisman, Mark
Krasemann, Susanne
Glatzel, Markus
Johnson, Keith A.
Sperling, Reisa A.
Reiman, Eric M.
Arboleda-Velasquez, Joseph F.
Kosik, Kenneth S.
Lopera, Francisco
Quiroz, Yakeel T.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9381462
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9381462
Other Identifiers
ISSN
0001-6322,1432-0533
E-ISSN
1432-0533
DOI
10.1007/s00401-022-02467-8
