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Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution

Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9387688

Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution

About this item

Full title

Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution

Publisher

US: Oxford University Press

Journal title

The journal of clinical endocrinology and metabolism, 2022-09, Vol.107 (9), p.2439-2448

Language

English

Formats

Publication information

Publisher

US: Oxford University Press

More information

Scope and Contents

Contents

Abstract
Context
The adrenal cortex consists of zona glomerulosa (ZG), fasciculata (ZF), and reticularis. Aldosterone-producing cell clusters (APCCs) that strongly express aldosterone synthase (CYP11B2) are frequently found in adult adrenals and harbor somatic mutations that are also detected in aldosterone-producing adenomas (APAs). Primary...

Alternative Titles

Full title

Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9387688

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9387688

Other Identifiers

ISSN

0021-972X

E-ISSN

1945-7197

DOI

10.1210/clinem/dgac394

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