Detection of early seeding of Richter transformation in chronic lymphocytic leukemia
Detection of early seeding of Richter transformation in chronic lymphocytic leukemia
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Author / Creator
Nadeu, Ferran , Royo, Romina , Massoni-Badosa, Ramon , Playa-Albinyana, Heribert , Garcia-Torre, Beatriz , Duran-Ferrer, Martí , Dawson, Kevin J. , Kulis, Marta , Diaz-Navarro, Ander , Villamor, Neus , Melero, Juan L. , Chapaprieta, Vicente , Dueso-Barroso, Ana , Delgado, Julio , Moia, Riccardo , Ruiz-Gil, Sara , Marchese, Domenica , Giró, Ariadna , Verdaguer-Dot, Núria , Romo, Mónica , Clot, Guillem , Rozman, Maria , Frigola, Gerard , Rivas-Delgado, Alfredo , Baumann, Tycho , Alcoceba, Miguel , González, Marcos , Climent, Fina , Abrisqueta, Pau , Castellví, Josep , Bosch, Francesc , Aymerich, Marta , Enjuanes, Anna , Ruiz-Gaspà, Sílvia , López-Guillermo, Armando , Jares, Pedro , Beà, Sílvia , Capella-Gutierrez, Salvador , Gelpí, Josep Ll , López-Bigas, Núria , Torrents, David , Campbell, Peter J. , Gut, Ivo , Rossi, Davide , Gaidano, Gianluca , Puente, Xose S. , Garcia-Roves, Pablo M. , Colomer, Dolors , Heyn, Holger , Maura, Francesco , Martín-Subero, José I. and Campo, Elías
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Richter transformation (RT) is a paradigmatic evolution of chronic lymphocytic leukemia (CLL) into a very aggressive large B cell lymphoma conferring a dismal prognosis. The mechanisms driving RT remain largely unknown. We characterized the whole genome, epigenome and transcriptome, combined with single-cell DNA/RNA-sequencing analyses and function...
Alternative Titles
Full title
Detection of early seeding of Richter transformation in chronic lymphocytic leukemia
Authors, Artists and Contributors
Author / Creator
Royo, Romina
Massoni-Badosa, Ramon
Playa-Albinyana, Heribert
Garcia-Torre, Beatriz
Duran-Ferrer, Martí
Dawson, Kevin J.
Kulis, Marta
Diaz-Navarro, Ander
Villamor, Neus
Melero, Juan L.
Chapaprieta, Vicente
Dueso-Barroso, Ana
Delgado, Julio
Moia, Riccardo
Ruiz-Gil, Sara
Marchese, Domenica
Giró, Ariadna
Verdaguer-Dot, Núria
Romo, Mónica
Clot, Guillem
Rozman, Maria
Frigola, Gerard
Rivas-Delgado, Alfredo
Baumann, Tycho
Alcoceba, Miguel
González, Marcos
Climent, Fina
Abrisqueta, Pau
Castellví, Josep
Bosch, Francesc
Aymerich, Marta
Enjuanes, Anna
Ruiz-Gaspà, Sílvia
López-Guillermo, Armando
Jares, Pedro
Beà, Sílvia
Capella-Gutierrez, Salvador
Gelpí, Josep Ll
López-Bigas, Núria
Torrents, David
Campbell, Peter J.
Gut, Ivo
Rossi, Davide
Gaidano, Gianluca
Puente, Xose S.
Garcia-Roves, Pablo M.
Colomer, Dolors
Heyn, Holger
Maura, Francesco
Martín-Subero, José I.
Campo, Elías
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9388377
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9388377
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-022-01927-8
