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Advances in covalent drug discovery

Advances in covalent drug discovery

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9403961

Advances in covalent drug discovery

About this item

Full title

Advances in covalent drug discovery

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Drug discovery, 2022-12, Vol.21 (12), p.881-898

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Covalent drugs have been used to treat diseases for more than a century, but tools that facilitate the rational design of covalent drugs have emerged more recently. The purposeful addition of reactive functional groups to existing ligands can enable potent and selective inhibition of target proteins, as demonstrated by the covalent epidermal growth...

Alternative Titles

Full title

Advances in covalent drug discovery

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9403961

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9403961

Other Identifiers

ISSN

1474-1776

E-ISSN

1474-1784

DOI

10.1038/s41573-022-00542-z

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