Mechanisms and inhibition of Porcupine-mediated Wnt acylation
Mechanisms and inhibition of Porcupine-mediated Wnt acylation
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Wnt signalling is essential for regulation of embryonic development and adult tissue homeostasis
1
–
3
, and aberrant Wnt signalling is frequently associated with cancers
4
. Wnt signalling requires palmitoleoylation on a hairpin 2 motif by the endoplasmic reticulum-resident membrane-bound
O
-acyltransferase Porcupine
5
Alternative Titles
Full title
Mechanisms and inhibition of Porcupine-mediated Wnt acylation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9404457
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9404457
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04952-2
