Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a no...
Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Proteins expressed by the paired box gene 9 (PAX9) and Msh Homeobox 1 (MSX1) are intimately involved in tooth development (odontogenesis). The regulation of PAX9 and MSX1 protein turnover by deubiquitinating enzymes (DUBs) plausibly maintain the required levels of PAX9 and MSX1 during odontogenesis. Herein, we used a loss-of-function CRISPR-Cas9-me...
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Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9433428
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9433428
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/s41418-022-00956-7
