Pharmacodynamic effect of bempedoic acid and statin combinations: predictions from a dose–response m...
Pharmacodynamic effect of bempedoic acid and statin combinations: predictions from a dose–response model
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Publisher
England: Oxford University Press
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Language
English
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Publisher
England: Oxford University Press
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Abstract
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Many patients are unable to achieve guideline-recommended LDL cholesterol (LDL-C) targets, despite taking maximally tolerated lipid-lowering therapy. Bempedoic acid, a competitive inhibitor of ATP citrate lyase, significantly lowers LDL-C with or without background statin therapy in diverse populations. Because pharmacodynamic i...
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Full title
Pharmacodynamic effect of bempedoic acid and statin combinations: predictions from a dose–response model
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9440868
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9440868
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ISSN
2055-6837,2055-6845
E-ISSN
2055-6845
DOI
10.1093/ehjcvp/pvab064
